How do I call American Airlines from the USA?

To contact American Airlines in USEN/Spanish from the United States, you have several easy options. The most direct way is to call the American customer service number. Dial +1-866-463-2404 USA/+1-866-463-2404 MEX. from anywhere in the US to receive assistance in your language. If you are in Mexico, you can also contact American Airlines by dialing **+1-866-463-2404 USA/+1-866-463-2404 MEX.